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China HA-1100 Hydroxyfasudil cas 105628-72-6 for sale

HA-1100 Hydroxyfasudil cas 105628-72-6

Price Negotiable
Price: Negotiable
MOQ: 1g
Delivery Time: Negotiable
Brand: Crene
Product Description
Chemical Information
Product name:HA-1100 Hydroxyfasudil Purity:98% min
CAS NO:105628-72-6 Solubility:DMSO : ≥ 31 mg/mL (100.86 mM)
Molecular Formula:C14H17N3O3S Package:Package according to customer requirements
Molecular Weight:307.368 Storage:Store at -20℃
Remarks

Hydroxyfasudil (HA-1100), an active metabolite of fasudil hydrochloride, is a specific Rho-kinase(ROCK) inhibitor with IC50 values of 0.73 μM and 0.72 μM for ROCK1 and ROCK2, respectively.

 

 

 

 

PKC Inhibitors Related Products:

GSK690693; Staurosporine; Valrubicin; ML-7 HCl; Midostaurin; Go6976; TAS-301; Fasudil; Fasudil (HA-1077) HCl; Enzastaurin

References

[1]. Rikitake Y, et al. Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke. 2005 Oct;36(10):2251-7. Epub 2005 Sep 1.

[2]. Masago T, et al. Effect of the rho-kinase inhibitor hydroxyfasudil on bladder overactivity: an experimental rat model. Int J Urol. 2009 Oct;16(10):842-7.

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Company Taizhou Crene Biotechnology Co., Ltd.
Location Add: Economic Developed Zone of Taizhou Zhejiang China.

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