Daptomycin Lipopeptide Antibiotic Cas 103060-53-3

Daptomycin is a lipopeptide antibiotic used in the treatment of systemic and life-threatening infections caused by Gram-positive organisms. It is a naturally occurring compound found in the soil saprotroph Streptomyces roseosporus. Its distinct mechanism of action makes it useful in treating infections caused by multiple drug-resistant bacteria. It is marketed in the United States under the trade name Cubicin by Cubist Pharmaceuticals.

Properties:

Appearance & Physical State: White powder

Density: 1.45 g/cm3

Boiling Point: 2078.2ºC at 760 mmHg

Flash Point: 1210.7ºC

Refractive Index: 1.638

Vapor Pressure: 0mmHg at 25°C

Related Prodcuts:

Cisplatin; Gemcitabine HCL; Bleomycin Sulfate; Temozolomide; Carmustine; CX-5461; Fludarabine Phosphate; Nelarabine; Cladribine; Trifluridine

[1] Silverman JA, et al. Antimicrob Agents Chemother, 2003, 47(8), 2538-2544.

[2] Rybak MJ, et al. Antimicrob Agents Chemother, 2000, 44(4), 1062-1066.

[3] Steenbergen JN, et al. J Antimicrob Chemother, 2005, 55(3), 283-288.