ABT-578 Zotarolimus MTOR Inhibitors Cas 221877-54-9
ABT-578 Zotarolimus MTOR Inhibitors Cas 221877-54-9
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Chemical Information
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Product name:ABT-578 Zotarolimus |
Purity:98% min |
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CAS NO:221877-54-9 |
Solubility:DMSO100 mg/mL (103.50 mM) |
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Molecular Formula:C52H79N5O12 |
Package:Package according to customer requirements. |
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Molecular Weight:966.21 |
Storage:Store at -20℃ |
Quality control
COA
Remarks
Zotarolimus, also known as ABT-578 and A-179578, is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. Medtronic are using zotarolimus as the anti-proliferative agent in the polymer coating of their Endeavor and Resolute products.
Related Prodcuts:
Tacrolimus; AZD8055; AZD8055 fumarate; OSI-027; Vistusertib; Zotarolimus; XL388; INK 128; PP121; Desmethyl-VS-5584; AZD-8055
References
[1].Wagner R et al. Rapamycin analogs with reduced systemic exposure. et al. Bioorg Med Chem Lett. 2005 Dec 1, 15(23), 5340-3.
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