KGA-2727 cas 666842-36-0
Price:
Negotiable
MOQ:
1g
Delivery Time:
Negotiable
Brand:
Crene
Product Description
Chemical Information
| Product name:KGA-2727 | Purity:98.0% min |
| CAS NO:666842-36-0 | Solubility:DMSO : 100 mg/mL (186.35 mM; Need ultrasonic) |
| Molecular Formula:C26H40N4O8 | Package:Package according to customer requirements |
| Molecular Weight:536.63 | Storage:Store at -20℃ |
Remarks
KGA-2727 is a potent, selective, high-affinity inhibitor of sodium glucose cotransporter 1 (SGLT1) with Ki of 97.4 nM and 43.5 nM for human SGLT1 and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 exhibits antidiabetic efficacy in rodent models.
Properties:
Boiling point: 839.6±65.0 °C(Predicted)
density: 1.308±0.06 g/cm3(Predicted)
pka: 12.65±0.70(Predicted)
SGLT Inhibitors Related Prodcuts:
Canagliflozin; Empagliflozin; Sotagliflozin; Ertugliflozin; Dapagliflozin
References
[1] Shibazaki T, et al. J Pharmacol Exp Ther. 2012 Aug;342(2):28
Similar Products
Get in Touch
Have questions about our products or want to discuss a custom order? Our team is ready to help you.
Company
Taizhou Crene Biotechnology Co., Ltd.
Location
Add: Economic Developed Zone of Taizhou Zhejiang China.