TPX-0022 CSF1R-IN-2 cas 2271119-26-5
Price:
Negotiable
MOQ:
1g
Delivery Time:
Negotiable
Brand:
Crene
Product Description
Chemical Information
| Product name:TPX-0022 CSF1R-IN-2 | Purity:98.0% min |
| CAS NO:2271119-26-5 | Solubility:DMSO : 25 mg/mL (61.06 mM; Need ultrasonic) |
| Molecular Formula:C20H20FN7O2 | Package:Package according to customer requirements |
| Molecular Weight:409.42 | Storage:Store at -20℃ |
Remarks
TPX-0022, also known as CSF1R-IN-2, is an orally bioavailable multi-targeted kinase inhibitor with a novel three-dimensional macrocyclic structure that inhibits the MET, CSF1R (colony stimulating factor 1 receptor) and SRC kinases. Targeting CSF1R leads to the modulation of tumor-associated macrophages (TAMs), a type of immune cell that suppresses the T-cell mediated anti-tumor immune response. Inhibition of CSF1R with TPX-0022 is a promising therapeutic strategy as a single agent or in combination with standard of care chemotherapy and immunotherapy in various solid tumors
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Company
Taizhou Crene Biotechnology Co., Ltd.
Location
Add: Economic Developed Zone of Taizhou Zhejiang China.