Bempedoic acid cas 738606-46-7

Name: Bempedoic acid cas 738606-46-7
Brand: Taizhou Crene Biotechnology Co., Ltd.

Price Negotiable

Price: Negotiable

MOQ: 1g

Delivery Time: Negotiable

Brand: Crene

Product Description

Chemical Information

Product name:Bempedoic acid	Purity:98% min
CAS NO:738606-46-7	Solubility:DMSO : 100 mg/mL (290.28 mM)
Molecular Formula:C₁₉H₃₆O₅	Package:Package according to customer requirements
Molecular Weight:344.486	Storage:Store at -20℃

Remarks

Bempedoic acid, also known as ESP-55016 and ETC-1002, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic acid is absorbed rapidly in the small intestine and enters the liver through cell surface receptors different from those transporters that selectively take up statins. Bempedoic acid is a regulator of lipid and carbohydrate metabolism.

Properties:

Boiling point: 506.5±35.0 °C(Predicted)

density: 1.045±0.06 g/cm3(Predicted)

pka: 4.55±0.45(Predicted)

ATP-citrate lyase inhibitor Related Products:

BMS-303141

References

[1]. Pinkosky SL, et al. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan;54(1):134-51.

[2]. Filippov S, et al. ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK. J Lipid Res. 2013 Aug;54(8):2095-108.