Selpercatinib LOXO-292 cas 2152628-33-4

Name: Selpercatinib LOXO-292 cas 2152628-33-4
Brand: Taizhou Crene Biotechnology Co., Ltd.

Price Negotiable

Price: Negotiable

MOQ: 1g

Delivery Time: Negotiable

Brand: Crene

Product Description

Chemical Information

Product name:Selpercatinib LOXO-292	Purity:98.0% min
CAS NO:2152628-33-4	Solubility:DMSO : 62.5 mg/mL (118.91 mM)
Molecular Formula:C₂₉H₃₁N₇O₃	Package:Package according to customer requirements
Molecular Weight:525.602	Storage:Store at -20℃

Remarks

Selpercatinib, also known as LOXO-292, is a potent and selective RET inhibitor with antineoplastic properties. LOXO-292 selectively binds to and targets various RET mutants and RET-containing fusion products. This results in an inhibition of cell growth of tumors cells that exhibit increased RET activity. Selpercatinib was approved in May 2020.

References

[1]. Steven W. Andrews, et al. Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors. WO2018071447A1.

[2].