ARV-110 cas 2222112-77-6
Price:
Negotiable
MOQ:
1g
Delivery Time:
Negotiable
Brand:
Crene
Product Description
Chemical Information
| Product name:ARV-110 | Purity:98.0% min |
| CAS NO:2222112-77-6 | Solubility:DMSO:100 mg/mL (123.1 mM) |
| Molecular Formula:C41H43ClFN9O6 | Package:Package according to customer requirements. |
| Molecular Weight:812.29 | Storage:Store at -20℃ |
Remarks
ARV-110 is a first-in-class PROTAC that effectively targets the wild type Androgen Receptor (AR) and certain genomic alterations of the AR (amplification, T878A, H875Y, F877L, M895V, but not L702H or AR-V7) for degradation in both enzalutamide sensitive and resistant preclinical models. ARV-110 showed promising anti-tumor activity in heavily pretreated men with metastatic castration-resistant prostate cancer (mCRPC).
Androgen Receptor Inhibitors Related Products:
Chlormadinone acetate; Bicalutamide; Apalutamide; Galeterone; Cyproterone acetate; AZD-3514; Spironolactone; Darolutamide; Megestrol Acetate; Clascoterone; RU-58841; Enzalutamide
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Company
Taizhou Crene Biotechnology Co., Ltd.
Location
Add: Economic Developed Zone of Taizhou Zhejiang China.