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Chemicals Organic Intermediate

tert-Butyl 1-piperazinecarboxylate cas 57260-71-6

Price Negotiable
Price: Negotiable
MOQ: 1g
Delivery Time: Negotiable
Brand: Crene
Product Description
Chemical Information
Product name:tert-Butyl 1-piperazinecarboxylate Purity:98% min
CAS NO:57260-71-6 Solubility:Soluble in DMSO
Molecular Formula:C9H18N2O2 Package:Package according to customer requirements.
Molecular Weight:186.251 Storage:-20ºC
Remarks

N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183).

 

Synonyms:

piperazine-1-carboxylic acid tert-butyl ester;

BOC-PIPERAZINE;

1-Boc piperzine;

t-Butyl 1-piperazincarboxylate;

1,1-Dimethylethyl 1-piperazinecarboxylate;

N-BOC-PIPERAZINE;

tert-butyl l-piperazinecarboxylate

 

Properties:

Appearance & Physical State: white or yellowish crystal

Density: 1.03 g/cm3

Boiling Point: 258ºC at 760 mmHg

Melting Point: 47-49ºC

Flash Point: 109.8ºC

Vapor Pressure: 0.0141mmHg at 25°C

References
[1]. Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.

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