LOXO-101 ARRY-470 Larotrectinib Sulfate Cas 1223405-08-0
Price:
Negotiable
MOQ:
1g
Delivery Time:
Negotiable
Brand:
Crene
Product Description
LOXO-101 ARRY-470 Larotrectinib Sulfate Cas 1223405-08-0
Chemical Information
| Product name:Larotrectinib sulfate | Purity:98% min |
| CAS NO:1223405-08-0 | Solubility:DMSO : 100 mg/mL (189.92 mM) |
| Molecular Formula:C21H24F2N6O6S | Package:Package according to customer requirements |
| Molecular Weight:526.514 | Storage:-20 ℃ |
Remarks
Larotrectinib sulfate (LOXO-101, ARRY-470) is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest.
Trk receptor Inhibitors Related Products:
SP600125; Danusertib; GW441756; Altiratinib; GNF-5837; Ropotrectinib; Entrectinib; ANA-12
References
- [1] Ghilardi JR, et al. Mol Pain. 2010, 6:87.
- [2] Vaishnavi A, et al. Nat Med. 2013, 19(11):1469-72.
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Company
Taizhou Crene Biotechnology Co., Ltd.
Location
Add: Economic Developed Zone of Taizhou Zhejiang China.