TMP778 cas 1422171-08-1
Price:
Negotiable
MOQ:
1g
Delivery Time:
Negotiable
Brand:
Crene
Product Description
Chemical Information
| Product name:TMP778 | Purity:98% min |
| CAS NO:1422171-08-1 | Solubility: |
| Molecular Formula:C31H30N2O4 | Package:Package according to customer requirements |
| Molecular Weight:494.581 | Storage:-20 ℃ |
Remarks
TMP778 is a potent and selective RORγt inhibitor that suppresses experimental autoimmune uveitis development, but affects both Th17 and Th1 cell populations.
References
[1]. Skepner J, et al. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo. J Immunol. 2014 Mar 15;192(6):2564-75. [2]. Xiao S, et al. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity. 2014 Apr 17;40(4):477-89.
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Company
Taizhou Crene Biotechnology Co., Ltd.
Location
Add: Economic Developed Zone of Taizhou Zhejiang China.