BGC-20-1531 cas 1186532-61-5
| Product name:BGC-20-1531 | Purity:98% min |
| CAS NO:1186532-61-5 | Solubility: |
| Molecular Formula:C26H23N2NaO6S | Package:Package according to customer requirements |
| Molecular Weight:514.525 | Storage:-20 ℃ |
BGC201531, also known as GTPL3380 and AP-1531, is a EP4 antagonist for the treatment of acute migraine.
1: Antonova M, Wienecke T, Maubach K, Thomas E, Olesen J, Ashina M. The pharmacological effect of BGC20-1531, a novel prostanoid EP4 receptor antagonist, in the prostaglandin E2 human model of headache. J Headache Pain. 2011 Oct;12(5):551-9. doi: 10.1007/s10194-011-0358-9. Epub 2011 Jun 17. PubMed PMID: 21681585; PubMed Central PMCID: PMC3173651.
2: Maubach KA, Davis RJ, Clark DE, Fenton G, Lockey PM, Clark KL, Oxford AW, Hagan RM, Routledge C, Coleman RA. BGC20-1531, a novel, potent and selective prostanoid EP receptor antagonist: a putative new treatment for migraine headache. Br J Pharmacol. 2009 Jan;156(2):316-27. doi: 10.1111/j.1476-5381.2009.00027.x. Epub 2009 Jan 19. PubMed PMID: 19154437; PubMed Central PMCID: PMC2697835.
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