Shield-1 cas 914805-33-7

Name: Shield-1 cas 914805-33-7
Brand: Taizhou Crene Biotechnology Co., Ltd.

Price Negotiable

Price: Negotiable

MOQ: 1g

Delivery Time: Negotiable

Brand: Crene

Product Description

Chemical Information

Product name:Shield-1	Purity:98% min
CAS NO:914805-33-7	Solubility:DMSO : ≥ 250 mg/mL (333.82 mM)
Molecular Formula:C₄₂H₅₆N₂O₁₀	Package:Package according to customer requirements
Molecular Weight:748.901	Storage:-20 ℃

Remarks

Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP). Shield-1 reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 stabilizes the entire fusion protein.

References

[1]. Schoeber JP, et al. Conditional fast expression and function of multimeric TRPV5 channels using Shield-1. Am J Physiol Renal Physiol. 2009 Jan;296(1):F204-11.

[2]. Li S, et al. Effects of Shield1 on the viral replication of varicella zoster virus containing FKBP tagged ORF4and 48. Mol Med Rep. 2018 Jan;17(1):763-770.