Taizhou Crene Biotechnology Co., Ltd.
                                                                                                           
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Chemicals Organic Intermediate
China GW280264X Custom Chemical Synthesis ADAM17 inhibitor Cas 866924-39-2 for sale

GW280264X Custom Chemical Synthesis ADAM17 inhibitor Cas 866924-39-2

Price Negotiable
Price: Negotiable
MOQ: 1g
Delivery Time: Negotiable
Brand: Crene
Product Description

GW280264X Custom Chemical Synthesis ADAM17 inhibitor Cas 866924-39-2

 

Chemical Information
Product name:GW280264X Purity:98% min
CAS NO:866924-39-2 Solubility:
Molecular Formula:C28H41N5O6S Package:Package according to customer requirements
Molecular Weight:575.72 Storage:-20℃
Remarks

GW280264X is an ADAM17 inhibitor.

References

1: Yang J, LeBlanc ME, Cano I, Saez-Torres KL, Saint-Geniez M, Ng YS, D'Amore PA. ADAM10 and ADAM17 proteases mediate proinflammatory cytokine-induced and constitutive cleavage of endomucin from the endothelial surface. J Biol Chem. 2020 May 8;295(19):6641-6651. doi: 10.1074/jbc.RA119.011192. Epub 2020 Mar 19. PMID: 32193206; PMCID: PMC7212652.

2: Kouam PN, Rezniczek GA, Adamietz IA, Bühler H. Ionizing radiation increases the endothelial permeability and the transendothelial migration of tumor cells through ADAM10-activation and subsequent degradation of VE-cadherin. BMC Cancer. 2019 Oct 16;19(1):958. doi: 10.1186/s12885-019-6219-7. PMID: 31619190; PMCID: PMC6794838.

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Company Taizhou Crene Biotechnology Co., Ltd.
Location Add: Economic Developed Zone of Taizhou Zhejiang China.

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