Nisoxetine hydrochloride cas 57754-86-6

Name: Nisoxetine hydrochloride cas 57754-86-6
Brand: Taizhou Crene Biotechnology Co., Ltd.

Price Negotiable

Price: Negotiable

MOQ: 1g

Delivery Time: Negotiable

Brand: Crene

Product Description

Chemical Information

Product name:Nisoxetine hydrochloride	Purity:98% min
CAS NO:57754-86-6	Solubility:
Molecular Formula:C₁₇H₂₂ClNO₂	Package:Package according to customer requirements
Molecular Weight:307.815	Storage:-20℃

Remarks

Nisoxetine hydrochloride is a potent and selective noradrenaline transporter (NET) inhibitor with Kd of 0.76 nM. Nisoxetine hydrochloride is an antidepressant and local anesthetic that blocks voltage-gated sodium channels.

References

[1]. Béïque JC, et, al. Affinities of venlafaxine and various reuptake inhibitors for the serotonin and norepinephrine transporters. Eur J Pharmacol. 1998 May 15; 349(1): 129-32.

[2]. Cheetham SC, et, al. [3H]nisoxetine-a radioligand for noradrenaline reuptake sites: correlation with inhibition of [3H]noradrenaline uptake and effect of DSP-4 lesioning and antidepressant treatments. Neuropharmacology. 1996 Jan; 35(1): 63-70.