Protirelin cas 24305-27-9

Protirelin (Thyroliberin, Lopremone, Synthetic TRH, Thyrotropin-releasing hormone, Rifathyroin) is a tripeptide that stimulates the release of thyrotropin and prolactin.

Thyrotropin-releasing hormone (TRH), also called thyrotropin-releasing factor (TRF) or thyroliberin, is a releasing hormone, produced by the hypothalamus, that stimulates the release of thyrotropin (thyroid-stimulating hormone or TSH) and prolactin from the anterior pituitary. It is a tropic, tripeptidal hormone.

TRH has been used clinically for the treatment of spinocerebellar degeneration and disturbance of consciousness in humans. Its pharmaceutical form is called protirelin (INN).

Related Prodcuts:

Abaloparatide; Tetracosactide; Thymalfasin; Thymosin alpha 1; Thymosin beta 4; Triptorelin; Triptorelin Acetate; Vapreotide; Vasopressin; Ziconotide Acetate; Antide; Teduglutide; Eledoisin; Aviptadil; Teriparatide acetate

[1]. Van Sinay E, et al. Evolutionarily conserved TRH neuropeptide pathway regulates growth in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4065-E4074.

[2]. Noda Y, et al. Hyperthermia induced by thyrotropin-releasing hormone (TRH, Protirelin) in the rat. Kurume Med J. 1979;26(2):107-12.