SB 242084 hydrochloride cas 1049747-87-6

Name: SB 242084 hydrochloride cas 1049747-87-6
Brand: Taizhou Crene Biotechnology Co., Ltd.

Price Negotiable

Price: Negotiable

MOQ: 1g

Delivery Time: Negotiable

Brand: Crene

Product Description

Chemical Information

Product name:SB 242084 hydrochloride	Purity:98% min
CAS NO:1049747-87-6	Solubility:DMSO : ≥ 125.5 mg/mL (268.29 mM)
Molecular Formula:C₂₁H₂₁Cl₃N₄O₂	Package:Package according to customer requirements.
Molecular Weight:394.854	Storage:Store at -20 ℃

Remarks

SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.

References

[1]. Kennett GA, et al. SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology. 1997 Apr-May;36(4-5):609-20.

[2]. Bromidge SM, et al. 6-Chloro-5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]- indoline (SB-242084): the first selective and brain penetrant 5-HT2C receptor antagonist. J Med Chem. 1997 Oct 24;40(22):3494-6.