JNJ303 Active Ingredient Api In Pharmacy Cas 878489-28-2
Price:
Negotiable
MOQ:
1g
Delivery Time:
Negotiable
Brand:
Crene
Product Description
JNJ303 Active Ingredient Api In Pharmacy Cas 878489-28-2
Chemical Information
| Product name:JNJ303 | Purity:99% min |
| CAS NO:878489-28-2 | Solubility:DMSO : 62.5 mg/mL (141.73 mM) |
| Molecular Formula:C21H29ClN2O4S | Package:Package according to customer requirements |
| Molecular Weight:440.984 | Storage:Store at +4°C |
Quality control
COA
Remarks
JNJ 303 is a potent blocker of the voltage dependent IKs-channel encoded by KCNQ1/KCNE1 with IC50 of 64 nM. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP).
Chemical Name:
2-(4-chlorophenoxy)-N-[(1R,3S)-5-(methanesulfonamido)-2-adamantyl]-2-methylpropanamide
Potassium Channel Inhibitors Related Prodcuts:
Glimepiride; Vonoprazan Fumarate; Gliclazide; Almitrine dimesylate; Dofetilide; Dronedarone HCl; Mitiglinide Calcium; Glyburide
References
[1]. Julie Albrecht, et al. The effect of the KV7/KCNE 1 inhibitor JNJ 303 on heart slices and the L-type calcium channel of cardiac cells.
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Company
Taizhou Crene Biotechnology Co., Ltd.
Location
Add: Economic Developed Zone of Taizhou Zhejiang China.