NE-10790 3-PEHPC cas 152831-36-2

Name: NE-10790 3-PEHPC cas 152831-36-2
Brand: Taizhou Crene Biotechnology Co., Ltd.

Price Negotiable

Price: Negotiable

MOQ: 1g

Delivery Time: Negotiable

Brand: Crene

Product Description

Chemical Information

Product name:NE-10790 3-PEHPC	Purity:98% min
CAS NO:152831-36-2	Solubility:H2O : 5 mg/mL (20.23 mM)
Molecular Formula:C₈H₁₀NO₆P	Package:Package according to customer requirements.
Molecular Weight:247.142	Storage:-20 ℃

Remarks

NE10790 is a risedronate analog, which belongs to the group of phosphonocarboxylates in which one of the phosphonate groups is substituted by a carboxyl group. NE-10790 had strongly reduced binding affinity, but still retained some antiresorptive activity. The group of phosphonocarboxylates, with strongly reduced bone affinity, provides an interesting therapeutic option.

References

[1]. Coxon FP, et al. Identification of a novel phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase that specifically prevents Rab prenylation in osteoclasts and macrophages. J Biol Chem. 2001 Dec 21;276(51):48213-22.