ED-71 Eldecalcitol cas 104121-92-8

Eldecalcitol is a drug used in Japan for the treatment of osteoporosis. It is an analog of vitamin D. Eldecalcitol is an orally administered drug to patients, which binds to vitamin D receptors and binding protein for the goal of achieving greater specificity to bind calcium for its absorption. This greater affinity is 2.7-fold that of the active vitamin D form of calcitriol. Eldecalcitol is readily absorbed into the body, with a long elimination half-life of over eight hours, reaching maximum absorption in 3.4 hours.

Properties:

Density: 1.1g/cm3

Melting Point: 126-128ºC
Boiling Point: 655.7ºC at 760mmHg
Flash Point: 350.3ºC
Refractive Index: 1.55
Vapor Pressure: 5.68E-20mmHg at 25°C

Related Prodcuts:

Eldecalcitol Intermediates CD; Eldecalcitol Intermediates A; Eldecalcitol intermediates(66774-84-3; 200636-42-6)

[1]. Matsumoto T.Osteoporosis Treatment by a New Active Vitamin D3 Compound, Eldecalcitol, in Japan.Curr Osteoporos Rep. 2012 Aug 24.

[2]. Shiraki M, et al. Eldecalcitol normalizes bone turnover markers regardless of their pre-treatment levels.Curr Med Res Opin. 2012 Aug 23.