Active Pharmaceutical Ingredient

Chemical Information Product name:Maxacalcitol Purity:98% min CAS NO:103909-75-7 Solubility:DMSO : 100 mg/mL (238.89 mM) Molecular Formula:C26H42O4 Package:Package according to customer requirements. Molecular Weight:418.609 Storage:Store at -20℃ Quality control COA Remarks Maxacalcitol, also known as 22-Oxacalcitriol, is an analog of calcitriol that, like calcitriol, is a receptor-active form of vitamin D3 which effectively blocks PTH synthesis. Maxacalcitol (OCT) induces

Chemical Information Product name:Calcitriol Purity:98% min CAS NO:32222-06-3 Solubility:DMSO : ≥ 100 mg/mL (240.02 mM) Molecular Formula:C27H44O3 Package:Package according to customer requirements Molecular Weight:416.636 Storage:Store at -20℃ Quality control COA Remarks Calcitriol is the active form of vitamin D, normally made in the kidney. A manufactured form is used to treat kidney disease with low blood calcium, hyperparathyroidism due to kidney disease, low blood

Chemical Information Product name:CHR-6494 Purity:98% min CAS NO:1333377-65-3 Solubility:DMSO : 50 mg/mL (171.03 mM) Molecular Formula:C16H16N6 Package:Package according to customer requirements Molecular Weight:292.338 Storage:Store at -20℃ Remarks CHR-6494 is a potent and selective histone kinase Haspin inhibitor. CHR-6494 reduces H3T3ph levels in a dose-dependent manner and causes a mitotic catastrophe characterized by metaphase misalignment, spindle abnormalities and

Chemical Information Product name:LDN-192960 Purity:98% min CAS NO:184582-62-5 Solubility:Soluble in DMSO Molecular Formula:C18H20N2O2S Package:Package according to customer requirements Molecular Weight:328.429 Storage:Store at -20℃ Remarks A comparison of the profiles of LDN-192960 (compound 3) and 42 suggests that only six kinases, including haspin, are inhibited by both compounds ≥90% at 10 µM. LDN-192960 alone does not cause detectable mitotic exit in the mitotic

Chemical Information Product name:HA-1100 Hydroxyfasudil Purity:98% min CAS NO:105628-72-6 Solubility:DMSO : ≥ 31 mg/mL (100.86 mM) Molecular Formula:C14H17N3O3S Package:Package according to customer requirements Molecular Weight:307.368 Storage:Store at -20℃ Remarks Hydroxyfasudil (HA-1100), an active metabolite of fasudil hydrochloride, is a specific Rho-kinase(ROCK) inhibitor with IC50 values of 0.73 μM and 0.72 μM for ROCK1 and ROCK2, respectively. PKC Inhibitors Related

Chemical Information Product name:GW7647 Purity:98% min CAS NO:265129-71-3 Solubility:DMSO : ≥ 60 mg/mL (119.34 mM) Molecular Formula:C29H46N2O3S Package:Package according to customer requirements Molecular Weight:502.752 Storage:Store at -20℃ Remarks GW7647 (1 μM) causes a significant increase of PDZK1 protein expression to 129.7 ± 6.5% of vehicle treated control in Caco2BBE cells in the absence and presence of IL-1β. GW7647 also attenuates the IL-1β-mediated decrease in

Chemical Information Product name:MLN8237 Alisertib Purity:98% min CAS NO:1028486-01-2 Solubility:DMSO : 9.33 mg/mL (17.98 mM) Molecular Formula:C27H20ClFN4O4 Package:Package according to customer requirements. Molecular Weight:518.924 Storage:Store at -20℃ Remarks Alisertib, also known as MLN8237, is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity

Chemical Information Product name:INNO-206 Aldoxorubicin Purity:98% min CAS NO:151038-96-9 Solubility:Soluble in DMSO Molecular Formula:C37H42N4O13 Package:Package according to customer requirements Molecular Weight:750.748 Storage:Store at -20℃ Remarks Aldoxorubicin, also known as INNO-206 and Doxo-EMCH, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin with antineoplastic activity. INNO-206 binds selectively to the cysteine

Chemical Information Product name:AZD1152 Barasertib Purity:98% min CAS NO:722543-31-9 Solubility:DMSO : ≥ 33 mg/mL (56.17 mM) Molecular Formula:C26H31FN7O6P Package:Package according to customer requirements Molecular Weight:587.540 Storage:Store at -20℃ Remarks AZD1152 displays >3000-fold selectivity for Aurora B as compared with Aurora A which has an IC50 of 1.368 μM. AZD1152 has even less activity against 50 other serine-threonine and tyrosine kinases including FLT3, JAK2

Chemical Information Product name:VX-680 Tozasertib Purity:98% min CAS NO:639089-54-6 Solubility:DMSO : ≥ 106.67 mg/mL (229.60 mM) Molecular Formula:C23H28N8OS Package:Package according to customer requirements Molecular Weight:464.586 Storage:Store at -20℃ Quality control COA Remarks Tozasertib, also known as VX-680, MK0457 or VE465, is a synthetic, small-molecule Aurora kinase inhibitor with potential antitumor activity. Tozasertib binds to and inhibits Aurora kinases (AKs)

Chemical Information Product name:Epothilone D Purity:98% min CAS NO:189453-10-9 Solubility: DMSO : ≥ 320 mg/mL (650.83 mM) Molecular Formula:C26H39NO5S Package:Package according to customer requirements Molecular Weight:477.657 Storage:Store at -20℃ Remarks Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in

Chemical Information Product name:GW843682X Purity:98% min CAS NO:660868-91-7 Solubility:DMSO : 33.33 mg/mL (69.81 mM) Molecular Formula:C22H18F3N3O4S Package:Package according to customer requirements Molecular Weight:477.456 Storage:Store at -20℃ Remarks GW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively). GW843682X inhibited the proliferation and induced apoptosis of 5-8F cells in a

Chemical Information Product name:MK-1775 adavosertib Purity:98% min CAS NO:955365-80-7 Solubility:DMSO: 18.75 mg/mL Molecular Formula:C27H32N8O2 Package:Package according to customer requirements Molecular Weight:500.595 Storage:Store at -20℃ Remarks MK-1775, also known as adavosertib, AZD-1775, is a WEE1 inhibitor, is also a small molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. MK-1775 selectively targets and inhibits WEE1,

Chemical Information Product name:ITF2357 Givinostat hydrochloride monohydrate Purity:98% min CAS NO:732302-99-7 Solubility:DMSO : ≥ 100 mg/mL (210.10 mM) Molecular Formula:C24H30ClN3O5 Package:Package according to customer requirements Molecular Weight:475.965 Storage:Store at -20℃ Remarks Givinostat or gavinostat, aslo known as ITF2357, is a potent and orally active histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic

Chemical Information Product name: 1,4-dihydro-7-methoxy-4-oxo-6-quinolinecarboxylic acid methyl ester Synonyms: methyl 7-methoxy-4-oxo-1,4-dihydroquinoline-6-carboxylate CAS No.: 205448-65-3 Molecular Formula: C12H11NO4 Molecular weight: 233.22 Technicel Data Appearance: off-white powder purity: 99.5%+ Solubility: Package: Package according to customer requirements Storage: Keep containers tightly closed. Store in a cool, dry area away from incompatible substances Shipping

Chemical Information Product name: 4-chloro-7-methoxyquinoline-6-carboxamide Synonyms: 7-methoxy-4-chloro-quinoline-6-carboxamide CAS No.: 417721-36-9 Molecular Formula: C11H9ClN2O2 Molecular weight: 236.654 Technicel Data Appearance: off-white powder purity: 99.5%+ Solubility: Package: Package according to customer requirements Storage: Keep containers tightly closed. Store in a cool, dry area away from incompatible substances Shipping condition: Transport at room temperatur

Chemical Information Product name:Tedizolid Purity:98% min CAS NO:856866-72-3 Solubility:DMSO : 10 mg/mL (27.00 mM) Molecular Formula:C17H15FN6O3 Package:Package according to customer requirements Molecular Weight:450.32 Storage:Store at -20℃ Quality control COA| NMR| HPLC Remarks Tedizolid, also known as TR-700, DA-7157, Torezolid, is an oxazolidinone-class antibiotic. Tedizolid has been approved by FDA on June 20, 2014, for the treatment of acute bacterial Skin and skin

Chemical Information Product name:Marbofloxacin Purity:98% min CAS NO:115550-35-1 Solubility:DMSO : ≥ 3.8 mg/mL (10.49 mM) Molecular Formula:C17H19FN4O4 Package:Package according to customer requirements Molecular Weight:362.356 Storage:Store at -20℃ Quality control COA Remarks Marbofloxacin is a carboxylic acid derivative third generation fluoroquinolone antibiotic. It is used in veterinary medicine under the trade names Marbocyl,Forcyl and Zeniquin. A formulation of

Chemical Information Product name:UD-CG115 Pimobendan Purity:98% min CAS NO:74150-27-9 Solubility:DMSO : 50 mg/mL (149.53 mM) Molecular Formula:C19H18N4O2 Package:Package according to customer requirements. Molecular Weight:334.372 Storage:Store at -20℃ Quality control COA Remarks Pimobendan is a veterinary medication. Pimobendan is both a calcium sensitizer and a selective inhibitor of phosphodiesterase III (PDE3) with positive inotropic and vasodilator effects. Pimobendan

Chemical Information Product name:SNS-032 BMS-387032 Purity:98% min CAS NO:345627-80-7 Solubility:DMSO : 33.33 mg/mL (87.59 mM) Molecular Formula:C17H24N4O2S2 Package:Package according to customer requirements Molecular Weight:380.528 Storage:Store at -20℃ Remarks SNS-032, also known as BMS-387032, is a 2-aminothiazole-derived, small-molecule cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. CDK inhibitor SNS-032 selectively binds to CDKs 2, 7,