Synthesis Inhibitors

Chemical Information Product name:2,2-Dimethylbutyryl chloride Purity:98% min CAS NO:5856-77-9 Solubility:Soluble in DMSO Molecular Formula:C6H11ClO Package:Package according to customer requirements. Molecular Weight:134.6 Storage:-20ºC Remarks Synonyms: 2,2-Dimethylbutyricacidchloride; 2,2-dimethylbutanoyl chloride; 2,2-DIMETHYLBUTYRYL CHLORIDE; Dimethylbutyrylchloride; 2,2-dimethylbutyl chloride; 2,2 DiMethylbutiryl chloride; simvastatin intermediate Properties: Boiling

Chemical Information Product name:Flecainide acetate Purity:98% min CAS NO:54143-56-5 Solubility:DMSO : 50 mg/mL (105.40 mM) Molecular Formula:C19H24F6N2O5 Package:Package according to customer requirements. Molecular Weight:474.395 Storage:2-8ºC Remarks Flecainide acetate (R-818) is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac

Chemical Information Product name:SSE15206 Purity:98% min CAS NO:1370046-40-4 Solubility:DMSO : 150 mg/mL (403.82 mM) Molecular Formula:C19H21N3O3S Package:Package according to customer requirements Molecular Weight:371.45 Storage:Store at -20℃ Remarks SSE15206 is a microtubule depolymerizing agent that overcomes multidrug resistance. SSE15206 has potent antiproliferative activities in cancer cell lines of different origins and overcomes resistance to microtubule-targeting

Chemical Information Product name:CID2858522 Purity:98% min CAS NO:758679-97-9 Solubility:10 mM in DMSO Molecular Formula:C28H39N3O3 Package:Package according to customer requirements Molecular Weight:465.628 Storage:Store at -20℃ Remarks CID2858522, also known as ML029, is a potent and selective inhibitor of NF-κB Activation (C50 value of 0.07 μM). CID2858522 specifically inhibits NF-kB activation downstream of protein kinsase C (PKC). CID2858522 may be useful to researchers

Chemical Information Product name:MRK003 Purity:98% min CAS NO:623165-93-5 Solubility:Soluble in DMSO Molecular Formula:C25H31F6N3O2S Package:Package according to customer requirements Molecular Weight:551.588 Storage:Store at -20℃ Remarks MRK003 is a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma. MRK003 treatment induced caspase-dependent apoptosis and inhibited proliferation of MM and NHL cell lines

Chemical Information Product name:CGS-21680 HCl Purity:98% min CAS NO:124182-57-6 Solubility:DMSO : ≥ 20 mg/mL (37.31 mM) Molecular Formula:C23H30ClN7O6 Package:Package according to customer requirements Molecular Weight:535.981 Storage:Store at -20℃ Remarks CGS-21680 is a specific adenosine A2A subtype receptor agonist. It is soluble up to 3.4 mg/mL in DMSO and 20 mg/mL in 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin. The chemical is currently used by researchers interested

Chemical Information Product name:sitafloxacin isomer I(SSR) Purity:98% min CAS NO:127254-11-9 Solubility:DMSO Molecular Formula:C19H18ClF2N3O3 Package:Package according to customer requirements Molecular Weight:409.814 Storage:Store at -20℃ Remarks Properties: Density: 1.63 Boiling Point: 629.221ºC at 760 mmHg Related Prodcuts: sitafloxacin isomer II(RSR); sitafloxacin isomer III(RRS); Sitafloxacin Hydrate

Chemical Information Product name:BRYOSTATIN 1 Purity:98% min CAS NO:83314-01-6 Solubility:Soluble in DMSO Molecular Formula:C47H68O17 Package:Package according to customer requirements Molecular Weight:905.033 Storage:Store at -20℃ Remarks Bryostatin 1 is a potent Protein Kinase C modulator isolated from the bryozoan Bugula neritina. Properties: Density: 1.27g/cm3 Boiling Point: 954.7ºC at 760 mmHg Flash Point: 270ºC Refractive Index: 1.564 Storage Condition: -20ºC

Chemical Information Product name:GSK256066 Purity:98% min CAS NO:801312-28-7 Solubility:DMSO : ≥ 5.2 mg/mL (10.03 mM) Molecular Formula:C27H26N4O5S Package:Package according to customer requirements Molecular Weight:518.584 Storage:Store at -20℃ Remarks GSK256066 is a potent and selective PDE4 inhibitor that can be given by inhalation, minimising the potential for side effects. GSK256066 demonstrated a protective effect on the EAR and LAR. GSK256066 is a slow and tight

Chemical Information Product name:VX-222 Lomibuvir Purity:98% min CAS NO:1026785-59-0 Solubility:DMSO : ≥ 32 mg/mL (71.81 mM) Molecular Formula:C25H35NO4S Package:Packaging according to customer requirements Molecular Weight:445.615 Storage:Store at -20℃ Remarks Lomibuvir, also known as VX-222, VCH-222 and VX22, is an nonnucleoside NS5B polymerase inhibitor. VX-222 inhibits the 1b/Con1 HCV subgenomic replicon, with 50% effective concentrations (EC(50)s) 5 nM. VX-222 binds to

Chemical Information Product name:5,6-trans-Cloprostenol Purity:95%min CAS NO:57968-81-7 Solubility:Soluble in DMSO Molecular Formula:C22H29ClO6 Package:Packaging according to customer requirements Molecular Weight:424.91 Storage:Store at -20℃ Quality control COA Remarks (+)-5-trans-16-m-chlorophenoxy tetranor Prostaglandin F2α Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and

Chemical Information Product name:VE-822 Berzosertib Purity:98% min CAS NO:1232416-25-9 Solubility:DMSO : ≥ 35 mg/mL (75.50 mM) Molecular Formula:C24H25N5O3S Package:Package according to customer requirements Molecular Weight:463.552 Storage:Store at -20℃ Remarks Berzosertib, also known as M6620, VE-822, VX-970, is an potent ATR inhibitor. VE-822 inhibited ATR in vitro and in vivo. VE-822 decreased maintenance of cell-cycle checkpoints, increased persistent DNA damage and

Chemical Information Product name:Vibegron Purity:98% min CAS NO:1190389-15-1 Solubility:Soluble in DMSO Molecular Formula:C26H28N4O3 Package:Package according to customer requirements. Molecular Weight:444.526 Storage:-20ºC Remarks Vibegron, also known as MK-4618, is a potent and selective Beta 3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder (OAB). Vibegron has no unacceptable toxicity in preclinical species. Vibegron is currently in Phase 3 human

Chemical Information Product name:ARV-110 Purity:98.0% min CAS NO:2222112-77-6 Solubility:DMSO:100 mg/mL (123.1 mM) Molecular Formula:C41H43ClFN9O6 Package:Package according to customer requirements. Molecular Weight:812.29 Storage:Store at -20℃ Remarks ARV-110 is a first-in-class PROTAC that effectively targets the wild type Androgen Receptor (AR) and certain genomic alterations of the AR (amplification, T878A, H875Y, F877L, M895V, but not L702H or AR-V7) for degradation in

Chemical Information Product name:EMA401 Olodanrigan Purity:98% min CAS NO:1316755-16-4 Solubility:DMSO : ≥ 34 mg/mL (66.98 mM) Molecular Formula:C32H29NO5 Package:Package according to customer requirements Molecular Weight:507.576 Storage:Store at -20℃ Remarks EMA401, a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. References [1].

Chemical Information Product name:CPI-268456 Purity:98% min CAS NO:1380087-86-4 Solubility: Molecular Formula:C20H15Cl2N3O2 Package:Package according to customer requirements Molecular Weight:400.258 Storage:Store at -20℃ Remarks CPI-268456 is a bioactive chemical. Synonyms: 4H-Isoxazolo[5,4-d][2]benzazepine-4-acetamide, 8-chloro-6-(4-chlorophenyl)-1-methyl-, (4S)-; 2-((4R)-8-chloro-6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide

Chemical Information Product name:4-Hydroxynonenal Purity:99.0% min CAS NO:75899-68-2 Solubility:DMSO : 250 mg/mL (1600.31 mM; Need ultrasonic) Molecular Formula:C9H16O2 Package:Package according to customer requirements Molecular Weight:156.222 Storage:Store at -20℃ Remarks 4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4

Chemical Information Product name:Nicousamide Pyrotinib Maleate Purity:98% min CAS NO:704881-43-6 Solubility:Soluble in DMSO Molecular Formula:C18H12N2O9 Package:Package according to customer requirements. Molecular Weight:400.29 Storage:-20 ℃ Remarks Nicousamide is a TGF-β inhibitor potentially for the treatment of renal insufficiency. HER2 Inhibitors Related Products: Tucatinib; Afatinib (BIBW2992) Dimaleate; Poziotinib; ARRY-380 analog; Trastuzumab; Canertinib; Lapatinib;

Chemical Information Product name:Antibiotic-202 Sibofimloc Purity:98% min CAS NO:1616113-45-1 Solubility:DMSO : ≥ 31 mg/mL (47.72 mM) Molecular Formula:C35H39NO11 Package:Package according to customer requirements Molecular Weight:649.684 Storage:Store at -20℃ Remarks Sibofimloc is an Escherichia coli fimbrial (FimH) adhesin inhibitor. Synonyms: VRT-1353385;Antibiotic-202;8,8'-(1'-Acetylspiro[9H-fluorene-9,4'-piperidine]-2,7-diyl)bis[2,6-anhydro-7,8-dideoxy-D-glycero-D-manno

Chemical Information Product name:Remodulin Treprostinil Purity:98% min CAS NO:81846-19-7 Solubility:DMSO : ≥ 125 mg/mL (320.09 mM) Molecular Formula:C23H34O5 Package:Package according to customer requirements. Molecular Weight:390.52 Storage:Store at -20℃ Quality control COA Remarks Treprostinil is a vasodilator that is used for the treatment of pulmonary arterial hypertension. Treprostinil is a synthetic analog of prostacyclin (PGI2). The inhaled form of treprostinil was